Sleep disorders like narcolepsy, obstructive sleep apnea (OSA), and shift work disorder (SWD) have the potential to profoundly affect daily life due to excessive daytime sleepiness (EDS). Medications such as Armodafinil and its generic alternative, Artvigil 150 mg, are prescribed to ensure wakefulness. This article explores the similarities and differences between Artvigil 150 mg and Armodafinil to assist in identifying the most appropriate choice for treating sleep disorders.
Understanding Armodafinil and Artvigil
Armodafinil is the R-enantiomer of Modafinil and is used to induce wakefulness in patients suffering from sleep disorders. It comes under brand names such as Nuvigil. Artvigil 150 mg is a generic formulation of Armodafinil made by HAB Pharma. Both drugs have the same active compound and are employed to treat the same ailments.
Efficacy in Treating Sleep Disorders
Narcolepsy
Armodafinil has shown considerable efficacy in enhancing wakefulness in narcolepsy patients. In a 12-week trial, patients on Armodafinil experienced enhanced sleep latency and decreased EDS versus placebo. Although direct studies on Artvigil are scarce, it being bioequivalent to Armodafinil indicates equal effectiveness.
Obstructive Sleep Apnea (OSA)
In patients with residual daytime sleepiness after CPAP therapy, Armodafinil has been successful in increasing wakefulness and daily functioning. Artvigil, being generic, should provide similar benefits.
Shift Work Disorder (SWD)
Armodafinil has demonstrated notable improvements in sleep latency and decreased sleepiness during night shifts and commutes in SWD patients. The efficacy of Artvigil in this regard is also assumed to be the same because it has the same active ingredient.
Pharmacokinetics and Duration of Action
Armodafinil possesses a longer half-life than Modafinil, ensuring prolonged wakefulness during the day. Such a property is advantageous for those who need prolonged alertness. Artvigil, which has Armodafinil in it, exhibits this pharmacokinetic profile.
Safety and Side Effects
Common side effects for both Armodafinil and Artvigil include:
Headache
Nausea
Dizziness
Insomnia
Serious adverse effects are rare but can include skin reactions and psychiatric symptoms. Both medications have a low potential for abuse and are classified as Schedule IV substances .
Cost and Accessibility
Artvigil 150 mg is usually less expensive than generic Armodafinil and hence is more cost-effective for most patients. However, supply might differ from place to place, and purchase should be ensured through authentic sources only.
