Retatrutide is a GGG tri-agonist peptide that targets the GLP-1 GIP and glucagon receptors. This unique receptor profile has been studied for its potential effects on metabolic processes including energy expenditure and nutrient utilization. Research has explored its role in pathways related to gastric emptying appetite regulation and the breakdown of stored energy sources highlighting its distinct approach compared to other GLP-1 receptor agonists.

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